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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PAPOLA All Species: 26.67
Human Site: S654 Identified Species: 53.33
UniProt: P51003 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51003 NP_116021.2 745 82843 S654 V G V K R T S S P H K E E S P
Chimpanzee Pan troglodytes XP_515496 714 80108 P621 V I P R I T T P H N P A Q G Q
Rhesus Macaque Macaca mulatta XP_001101831 825 90125 S602 V G V K R T S S P H K E E S P
Dog Lupus familis XP_537551 812 90509 S721 V G V K R T S S P H K E E S P
Cat Felis silvestris
Mouse Mus musculus Q61183 739 82291 S648 V G V K R T S S P N K E E S P
Rat Rattus norvegicus NP_001101526 739 82082 S648 V G V K R T S S P H K E E S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511509 736 82218 S645 V G V K R T S S P N K E E S P
Chicken Gallus gallus XP_421352 737 82879 S647 T A V K R T S S P H K E D S P
Frog Xenopus laevis P51004 715 80169 K624 P S P V A G V K R T S S P S N
Zebra Danio Brachydanio rerio NP_991321 723 80246 N633 R P A S A L E N E M T K K A K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393202 615 69546 V526 G N G N S G S V S P R N P G N
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P29468 568 64534 V479 I E N K K E K V D I H I P C T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 59.8 78.4 89.7 N.A. 95.5 95 N.A. 95.5 89.9 80.1 70.3 N.A. N.A. 49.7 N.A. N.A.
Protein Similarity: 100 72.6 80.7 90.1 N.A. 97.4 96.7 N.A. 96.9 93.8 86.3 80 N.A. N.A. 62.2 N.A. N.A.
P-Site Identity: 100 13.3 100 100 N.A. 93.3 100 N.A. 93.3 80 6.6 0 N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: 100 40 100 100 N.A. 100 100 N.A. 100 86.6 6.6 26.6 N.A. N.A. 13.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 33.1 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 49.4 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 9 0 17 0 0 0 0 0 0 9 0 9 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % C
% Asp: 0 0 0 0 0 0 0 0 9 0 0 0 9 0 0 % D
% Glu: 0 9 0 0 0 9 9 0 9 0 0 59 50 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 50 9 0 0 17 0 0 0 0 0 0 0 17 0 % G
% His: 0 0 0 0 0 0 0 0 9 42 9 0 0 0 0 % H
% Ile: 9 9 0 0 9 0 0 0 0 9 0 9 0 0 0 % I
% Lys: 0 0 0 67 9 0 9 9 0 0 59 9 9 0 9 % K
% Leu: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 9 0 0 0 0 0 % M
% Asn: 0 9 9 9 0 0 0 9 0 25 0 9 0 0 17 % N
% Pro: 9 9 17 0 0 0 0 9 59 9 9 0 25 0 59 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % Q
% Arg: 9 0 0 9 59 0 0 0 9 0 9 0 0 0 0 % R
% Ser: 0 9 0 9 9 0 67 59 9 0 9 9 0 67 0 % S
% Thr: 9 0 0 0 0 67 9 0 0 9 9 0 0 0 9 % T
% Val: 59 0 59 9 0 0 9 17 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _